Detalhe da pesquisa
1.
Structures of brain-derived 42-residue amyloid-ß fibril polymorphs with unusual molecular conformations and intermolecular interactions.
Proc Natl Acad Sci U S A
; 120(11): e2218831120, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36893281
2.
A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
EMBO J
; 40(8): e103811, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33644875
3.
Contribution of the catalytic dyad of SARS-CoV-2 main protease to binding covalent and noncovalent inhibitors.
J Biol Chem
; 299(7): 104886, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37271339
4.
Effects of an HIV-1 maturation inhibitor on the structure and dynamics of CA-SP1 junction helices in virus-like particles.
Proc Natl Acad Sci U S A
; 117(19): 10286-10293, 2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32341150
5.
Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease.
Proc Natl Acad Sci U S A
; 117(26): 15018-15027, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32527859
6.
MWC allosteric model explains unusual hemoglobin-oxygen binding curves from sickle cell drug binding.
Biophys J
; 120(12): 2543-2551, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932439
7.
Constraints on the Structure of Fibrils Formed by a Racemic Mixture of Amyloid-ß Peptides from Solid-State NMR, Electron Microscopy, and Theory.
J Am Chem Soc
; 143(33): 13299-13313, 2021 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34375097
8.
Probing the mechanism of inhibition of amyloid-ß(1-42)-induced neurotoxicity by the chaperonin GroEL.
Proc Natl Acad Sci U S A
; 115(51): E11924-E11932, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30509980
9.
Concentration-Dependent Structural Transition of the HIV-1 gp41 MPER Peptide into α-Helical Trimers.
Angew Chem Int Ed Engl
; 60(1): 166-170, 2021 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32916024
10.
Probing the Interaction between HIV-1 Protease and the Homodimeric p66/p66' Reverse Transcriptase Precursor by Double Electron-Electron Resonance EPR Spectroscopy.
Chembiochem
; 21(21): 3051-3055, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32558168
11.
Binding kinetics and substrate selectivity in HIV-1 protease-Gag interactions probed at atomic resolution by chemical exchange NMR.
Proc Natl Acad Sci U S A
; 114(46): E9855-E9862, 2017 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29087351
12.
Oligomerization of the tetramerization domain of p53 probed by two- and three-color single-molecule FRET.
Proc Natl Acad Sci U S A
; 114(33): E6812-E6821, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760960
13.
Diverse Folding Pathways of HIV-1 Protease Monomer on a Rugged Energy Landscape.
Biophys J
; 117(8): 1456-1466, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31587829
14.
Observation of ß-Amyloid Peptide Oligomerization by Pressure-Jump NMR Spectroscopy.
J Am Chem Soc
; 141(35): 13762-13766, 2019 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31432672
15.
Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator.
J Am Chem Soc
; 141(20): 8327-8338, 2019 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31042030
16.
Importance of time-ordered non-uniform sampling of multi-dimensional NMR spectra of Aß1-42 peptide under aggregating conditions.
J Biomol NMR
; 73(8-9): 429-441, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31407200
17.
Transient HIV-1 Gag-protease interactions revealed by paramagnetic NMR suggest origins of compensatory drug resistance mutations.
Proc Natl Acad Sci U S A
; 113(44): 12456-12461, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791180
18.
Tilted, Uninterrupted, Monomeric HIV-1 gp41 Transmembrane Helix from Residual Dipolar Couplings.
J Am Chem Soc
; 140(1): 34-37, 2018 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29277995
19.
Co-Evolutionary Fitness Landscapes for Sequence Design.
Angew Chem Int Ed Engl
; 57(20): 5674-5678, 2018 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29512300
20.
Dissociation of the trimeric gp41 ectodomain at the lipid-water interface suggests an active role in HIV-1 Env-mediated membrane fusion.
Proc Natl Acad Sci U S A
; 111(9): 3425-30, 2014 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550514